Radiation Treatment, ATM, BRCA1/2, and CHEK2*1100delC Pathogenic Variants and Risk of Contralateral Breast Cancer

Whether radiation therapy (RT) affects contralateral breast cancer (CBC) risk in women with pathogenic germline variants in moderate- to high-penetrance breast cancer–associated genes is unknown. In a population-based case-control study, we examined the association between RT; variants in ATM, BRCA1...

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Detalhes bibliográficos
Publicado no:J Natl Cancer Inst
Main Authors: Reiner, Anne S, Robson, Mark E, Mellemkjær, Lene, Tischkowitz, Marc, John, Esther M, Lynch, Charles F, Brooks, Jennifer D, Boice, John D, Knight, Julia A, Teraoka, Sharon N, Liang, Xiaolin, Woods, Meghan, Shen, Ronglai, Shore, Roy E, Stram, Daniel O, Thomas, Duncan C, Malone, Kathleen E, Bernstein, Leslie, Riaz, Nadeem, Woodward, Wendy, Powell, Simon, Goldgar, David, Concannon, Patrick, Bernstein, Jonine L
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7735763/
https://ncbi.nlm.nih.gov/pubmed/32119081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djaa031
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