Risk for contralateral breast cancer among carriers of the CHEK2(*)1100delC mutation in the WECARE Study

The protein encoded by the CHEK2 gene is involved in cellular repair of DNA damage. The truncating mutation, CHEK2(*)1100delC, seems to increase the risk for breast cancer. We investigated whether the CHEK2(*)1100delC mutation carrier status increases the risk for asynchronous contralateral breast c...

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Hauptverfasser: Mellemkjær, L, Dahl, C, Olsen, J H, Bertelsen, L, Guldberg, P, Christensen, J, Børresen-Dale, A-L, Stovall, M, Langholz, B, Bernstein, L, Lynch, C F, Malone, K E, Haile, R W, Andersson, M, Thomas, D C, Concannon, P, Capanu, M, Boice, J D, Bernstein, J L
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2008
Schlagworte:
Clinical Study
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2259175/
https://ncbi.nlm.nih.gov/pubmed/18253122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604228
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