YAP/TAZ deficiency reprograms macrophage phenotype and improves infarct healing and cardiac function after myocardial infarction

Adverse cardiac remodeling after myocardial infarction (MI) causes structural and functional changes in the heart leading to heart failure. The initial post-MI pro-inflammatory response followed by reparative or anti-inflammatory response is essential for minimizing the myocardial damage, healing, a...

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Udgivet i:PLoS Biol
Main Authors: Mia, Masum M., Cibi, Dasan Mary, Abdul Ghani, Siti Aishah Binte, Song, Weihua, Tee, Nicole, Ghosh, Sujoy, Mao, Junhao, Olson, Eric N., Singh, Manvendra K.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7735680/
https://ncbi.nlm.nih.gov/pubmed/33264286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000941
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