YAP/TAZ deficiency reprograms macrophage phenotype and improves infarct healing and cardiac function after myocardial infarction

Adverse cardiac remodeling after myocardial infarction (MI) causes structural and functional changes in the heart leading to heart failure. The initial post-MI pro-inflammatory response followed by reparative or anti-inflammatory response is essential for minimizing the myocardial damage, healing, a...

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Veröffentlicht in:PLoS Biol
Hauptverfasser: Mia, Masum M., Cibi, Dasan Mary, Abdul Ghani, Siti Aishah Binte, Song, Weihua, Tee, Nicole, Ghosh, Sujoy, Mao, Junhao, Olson, Eric N., Singh, Manvendra K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7735680/
https://ncbi.nlm.nih.gov/pubmed/33264286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000941
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