ELABELA ameliorates hypoxic/ischemic-induced bone mesenchymal stem cell apoptosis via alleviation of mitochondrial dysfunction and activation of PI3K/AKT and ERK1/2 pathways

BACKGROUND: Mesenchymal stem cells (MSCs) have exerted their brilliant potential to promote heart repair following myocardial infarction. However, low survival rate of MSCs after transplantation due to harsh conditions with hypoxic and ischemic stress limits their therapeutic efficiency in treating...

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Detalhes bibliográficos
Publicado no:Stem Cell Res Ther
Main Authors: Fu, Jiaying, Chen, Xuxiang, Liu, Xin, Xu, Daishi, Yang, Huan, Zeng, Chaotao, Long, Huibao, Zhou, Changqing, Wu, Haidong, Zheng, Guanghui, Wu, Hao, Wang, Wuming, Wang, Tong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7734864/
https://ncbi.nlm.nih.gov/pubmed/33317626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-02063-1
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