Staurosporine Analogs Via C–H Borylation

[Image: see text] Staurosporine is among the most potent naturally occurring kinase inhibitors isolated to date and has served as a lead compound for numerous drug development efforts in several therapeutic areas. Herein we report that C–H borylation chemistry provides access to analogs of staurospo...

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Publicat a:ACS Med Chem Lett
Autors principals: Gayler, Kevin M., Kong, Ke, Reisenauer, Keighley, Taube, Joseph H., Wood, John L.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2020
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7734790/
https://ncbi.nlm.nih.gov/pubmed/33335665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.0c00420
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