Intravenous alteplase for unknown time of onset stroke guided by advanced imaging: a systematic review and meta-analysis of individual patient data

BACKGROUND –: Stroke patients with unknown time of onset have been previously excluded from thrombolysis. We aimed to determine whether intravenous alteplase is safe and effective in these patients when salvageable tissue is identified using imaging biomarkers. METHODS –: We performed a systematic r...

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Detaylı Bibliyografya
Yayımlandı:Lancet
Asıl Yazarlar: Thomalla, Götz, Boutitie, Florent, Ma, Henry, Koga, Masatoshi, Ringleb, Peter, Schwamm, Lee H., Wu, Ona, Bendszus, Martin, Bladin, Christopher F, Campbell, Bruce C.V., Cheng, Bastian, Churilov, Leonid, Ebinger, Martin, Endres, Matthias, Fiebach, Jochen B., Fukuda-Doi, Mayumi, Inoue, Manabu, Kleinig, Timothy J., Latour, Lawrence L., Lemmens, Robin, Levi, Christopher R, Leys, Didier, Miwa, Kaori, Molina, Carlos A., Muir, Keith W., Nighoghossian, Norbert, Parsons, Mark W., Pedraza, Salvador, Schellinger, Peter D., Schwab, Stefan, Simonsen, Claus Z., Song, Shlee S., Thijs, Vincent, Toni, Danilo, Hsu, Chung Y., Wahlgren, Nils, Yamamoto, Haruko, Yassi, Nawaf, Yoshimura, Sohei, Warach, Steven, Hacke, Werner, Toyoda, Kazunori, Donnan, Geoffrey A., Davis, Stephen M., Gerloff, Christian
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7734592/
https://ncbi.nlm.nih.gov/pubmed/33176180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(20)32163-2
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