High flow nasal therapy versus noninvasive ventilation as initial ventilatory strategy in COPD exacerbation: a multicenter non-inferiority randomized trial

BACKGROUND: The efficacy and safety of high flow nasal therapy (HFNT) in patients with acute hypercapnic exacerbation of chronic obstructive pulmonary disease (AECOPD) are unclear. Our aim was to evaluate the short-term effect of HFNT versus NIV in patients with mild-to-moderate AECOPD, with the hyp...

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Dettagli Bibliografici
Pubblicato in:Crit Care
Autori principali: Cortegiani, Andrea, Longhini, Federico, Madotto, Fabiana, Groff, Paolo, Scala, Raffaele, Crimi, Claudia, Carlucci, Annalisa, Bruni, Andrea, Garofalo, Eugenio, Raineri, Santi Maurizio, Tonelli, Roberto, Comellini, Vittoria, Lupia, Enrico, Vetrugno, Luigi, Clini, Enrico, Giarratano, Antonino, Nava, Stefano, Navalesi, Paolo, Gregoretti, Cesare
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7734463/
https://ncbi.nlm.nih.gov/pubmed/33317579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-020-03409-0
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