High-flow nasal therapy versus noninvasive ventilation in COPD patients with mild-to-moderate hypercapnic acute respiratory failure: study protocol for a noninferiority randomized clinical trial

BACKGROUND: Noninvasive ventilation (NIV) is indicated to treat respiratory acidosis due to exacerbation of chronic obstructive pulmonary disease (COPD). Recent nonrandomized studies also demonstrated some physiological effects of high-flow nasal therapy (HFNT) in COPD patients. We designed a prospe...

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Dades bibliogràfiques
Publicat a:Trials
Autors principals: Cortegiani, Andrea, Longhini, Federico, Carlucci, Annalisa, Scala, Raffaele, Groff, Paolo, Bruni, Andrea, Garofalo, Eugenio, Taliani, Maria Rita, Maccari, Uberto, Vetrugno, Luigi, Lupia, Enrico, Misseri, Giovanni, Comellini, Vittoria, Giarratano, Antonino, Nava, Stefano, Navalesi, Paolo, Gregoretti, Cesare
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Study Protocol
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6647141/
https://ncbi.nlm.nih.gov/pubmed/31331372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-019-3514-1
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