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Epigenetic inactivation of IRX4 is responsible for acceleration of cell growth in human pancreatic cancer

Epigenetic gene silencing by aberrant DNA methylation is one of the important mechanisms leading to loss of key cellular pathways in tumorigenesis. Methyl‐CpG‐targeted transcriptional activation (MeTA) reactivates hypermethylation‐mediated silenced genes in a different way from DNA‐demethylating age...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Chakma, Kanchan, Gu, Zhaodi, Abudurexiti, Yakefujiang, Hata, Tatsuo, Motoi, Fuyuhiko, Unno, Michiaki, Horii, Akira, Fukushige, Shinichi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7734003/
https://ncbi.nlm.nih.gov/pubmed/32894817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14644
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