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Does mutated K-RAS oncogene attenuate the effect of Sulindac in colon cancer chemoprevention?

The non-steroidal anti-inflammatory drug (NSAID) Sulindac has been successfully used alone or in combination with other agents to suppress colon tumorigenesis in patients with genetic predisposition, and also showed its efficacy in prevention of sporadic colon adenomas. At the same time, some experi...

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書目詳細資料
發表在:Cancer Prev Res (Phila)
Main Authors: Rice, Photini FS., Ehrichs, Kevin G., Jones, Mykella S., Chen, Hwudarw, Hsu, Chiu-Hsieh, Abril, Edward R., Nagle, Raymond B., Besselsen, David G., Barton, Jennifer K., Ignatenko, Natalia A.
格式: Artigo
語言:Inglês
出版: 2017
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7733710/
https://ncbi.nlm.nih.gov/pubmed/29118162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-17-0230
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