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Molecular insights on cytochrome c and nucleotide regulation of apoptosome function and its implication in cancer
Cytochrome c (Cyt c) released from mitochondria interacts with Apaf-1 to form the heptameric apoptosome, which initiates the caspase cascade to execute apoptosis. Although lysine residue at 72 (K72) of Cyt c plays an important role in the Cyt c-Apaf-1 interaction, the underlying mechanism of interac...
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| 出版年: | Biochim Biophys Acta Mol Cell Res |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7733678/ https://ncbi.nlm.nih.gov/pubmed/31678591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2019.118573 |
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