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Structure-based dynamic analysis of the glycine cleavage system suggests key residues for control of a key reaction step

Molecular shuttles play decisive roles in many multi-enzyme systems such as the glycine cleavage system (GCS) for one-carbon (C1) metabolism. In GCS, a lipoate swinging arm containing an aminomethyl moiety is attached to protein H and serves as a molecular shuttle among different proteins. Protectio...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Zhang, Han, Li, Yuchen, Nie, Jinglei, Ren, Jie, Zeng, An-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7733448/
https://ncbi.nlm.nih.gov/pubmed/33311647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01401-6
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