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Formaldehyde formation in the glycine cleavage system and its use for an aldolase-based biosynthesis of 1,3-propanediol

Glycine cleavage system (GCS) occupies a key position in one-carbon (C1) metabolic pathway and receives great attention for the use of C1 carbons like formate and CO(2) via synthetic biology. In this work, we demonstrate that formaldehyde exists as a substantial byproduct of the GCS reaction cycle....

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Publicat a:J Biol Eng
Autors principals: Xu, Yingying, Meng, Hao, Ren, Jie, Zeng, An-Ping
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7227101/
https://ncbi.nlm.nih.gov/pubmed/32467727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13036-020-00237-2
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