Label-free vibrational imaging of different Aβ plaque types in Alzheimer’s disease reveals sequential events in plaque development

The neuropathology of Alzheimer’s disease (AD) is characterized by hyperphosphorylated tau neurofibrillary tangles (NFTs) and amyloid-beta (Aβ) plaques. Aβ plaques are hypothesized to follow a development sequence starting with diffuse plaques, which evolve into more compact plaques and finally matu...

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Библиографические подробности
Опубликовано в: :Acta Neuropathol Commun
Главные авторы: Röhr, Dominik, Boon, Baayla D. C., Schuler, Martin, Kremer, Kristin, Hoozemans, Jeroen J. M., Bouwman, Femke H., El-Mashtoly, Samir F., Nabers, Andreas, Großerueschkamp, Frederik, Rozemuller, Annemieke J. M., Gerwert, Klaus
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2020
Предметы:
Methodology Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7733282/
https://ncbi.nlm.nih.gov/pubmed/33308303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-01091-5
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