Label-free vibrational imaging of different Aβ plaque types in Alzheimer’s disease reveals sequential events in plaque development

The neuropathology of Alzheimer’s disease (AD) is characterized by hyperphosphorylated tau neurofibrillary tangles (NFTs) and amyloid-beta (Aβ) plaques. Aβ plaques are hypothesized to follow a development sequence starting with diffuse plaques, which evolve into more compact plaques and finally matu...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Röhr, Dominik, Boon, Baayla D. C., Schuler, Martin, Kremer, Kristin, Hoozemans, Jeroen J. M., Bouwman, Femke H., El-Mashtoly, Samir F., Nabers, Andreas, Großerueschkamp, Frederik, Rozemuller, Annemieke J. M., Gerwert, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Methodology Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7733282/
https://ncbi.nlm.nih.gov/pubmed/33308303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-01091-5
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