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Genetic and clinical phenotypic analysis of familial stapes sclerosis caused by an NOG mutation

BACKGROUND: The noggin protein encoded by the NOG gene can interfere with the binding of bone morphogenetic protein to its receptor, thus affecting bone and joint development. The symptoms include abnormal skeletal development and conductive deafness. METHODS: In a retrospective study, clinical data...

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Bibliografiske detaljer
Udgivet i:BMC Med Genomics
Main Authors: Yu, Rong, Jiang, Hongqun, Liao, Huihuang, Luo, Wugen
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7733265/
https://ncbi.nlm.nih.gov/pubmed/33308208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-020-00843-5
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