lncRNA GCAT1 is involved in premature ovarian insufficiency by regulating p27 translation in GCs via competitive binding to PTBP1

Dysfunction of granulosa cells (GCs) leading to follicle atresia has been extensively studied as a major cause of premature ovarian insufficiency (POI), but the regulatory role of long non-coding RNAs (lncRNAs) in this process is still poorly understood. Here, we show that the lncRNA LINC02690 or GC...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Li, Duan, Wang, Xiaoyan, Dang, Yujie, Zhang, Xinyue, Zhao, Shidou, Lu, Gang, Chan, Wai-Yee, Leung, Peter C.K., Qin, Yingying
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7733005/
https://ncbi.nlm.nih.gov/pubmed/33335798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.10.041
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