Long noncoding RNA HCP5 participates in premature ovarian insufficiency by transcriptionally regulating MSH5 and DNA damage repair via YB1

The genetic etiology of premature ovarian insufficiency (POI) has been well established to date, however, the role of long noncoding RNAs (lncRNAs) in POI is largely unknown. In this study, we identified a down-expressed lncRNA HCP5 in granulosa cells (GCs) from biochemical POI (bPOI) patients, whic...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Wang, Xiaoyan, Zhang, Xinyue, Dang, Yujie, Li, Duan, Lu, Gang, Chan, Wai-Yee, Leung, Peter C K, Zhao, Shidou, Qin, Yingying, Chen, Zi-Jiang
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
RNA and RNA-protein complexes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7192606/
https://ncbi.nlm.nih.gov/pubmed/32112110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa127
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