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Beyond repression of Nrf2: an update on Keap1

Nrf2 (NFE2L2 – nuclear factor (erythroid-derived 2)-like 2) is a transcription factor, which is repressed by interaction with a redox-sensitive protein Keap1 (Kelch-like ECH-associated protein 1). Deregulation of Nrf2 transcriptional activity has been described in the pathogenesis of multiple diseas...

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Bibliografiska uppgifter
I publikationen:Free Radic Biol Med
Huvudupphovsmän: Kopacz, Aleksandra, Kloska, Damian, Forman, Henry Jay, Jozkowicz, Alicja, Grochot-Przeczek, Anna
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7732858/
https://ncbi.nlm.nih.gov/pubmed/32234331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2020.03.023
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