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Piecewise All-Atom SMD Simulations Reveal Key Secondary Structures in Luciferase Unfolding Pathway

Although the folding of single-domain proteins is well characterized theoretically and experimentally, the folding of large multidomain proteins is less well known. Firefly luciferase, a 550 residue three-domain protein, has been commonly used as a substrate to study chaperone reactions and as a mod...

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Bibliografiset tiedot
Julkaisussa:Biophys J
Päätekijät: Zhang, Pan, Wang, David, Yang, Weitao, Marszalek, Piotr E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Biophysical Society 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7732773/
https://ncbi.nlm.nih.gov/pubmed/33130123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.10.023
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