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Simulating Force-Induced Conformational Transitions in Polysaccharides with the SMD Replica Exchange Method

Conventional steered molecular dynamics (SMD) simulations do not readily reproduce equilibrium conditions of atomic force microscopy (AFM) stretch and release measurements of polysaccharides undergoing force-induced conformational transitions because of the gap between the timescales of computer sim...

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Detalhes bibliográficos
Main Authors: Lu, Zhenyu, Hu, Hao, Yang, Weitao, Marszalek, Piotr E.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1557546/
https://ncbi.nlm.nih.gov/pubmed/16829559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.090324
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