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Simulating Force-Induced Conformational Transitions in Polysaccharides with the SMD Replica Exchange Method

Conventional steered molecular dynamics (SMD) simulations do not readily reproduce equilibrium conditions of atomic force microscopy (AFM) stretch and release measurements of polysaccharides undergoing force-induced conformational transitions because of the gap between the timescales of computer sim...

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Détails bibliographiques
Auteurs principaux: Lu, Zhenyu, Hu, Hao, Yang, Weitao, Marszalek, Piotr E.
Format: Artigo
Langue:Inglês
Publié: Biophysical Society 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1557546/
https://ncbi.nlm.nih.gov/pubmed/16829559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.090324
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