27-Hydroxycholesterol Promotes the Transfer of Astrocyte-Derived Cholesterol to Neurons in Co-cultured SH-SY5Y Cells and C6 Cells

Abnormality in cholesterol homeostasis in the brain is a feature of Alzheimer’s disease (AD). 27-Hydroxycholesterol (27-OHC) has been identified as a possible biomarker of AD, but its effects on cholesterol metabolism have not been fully characterized. This study was aimed to investigate the impacts...

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Bibliographische Detailangaben
Veröffentlicht in:Front Cell Dev Biol
Hauptverfasser: Wang, Yushan, Zhang, Xiaona, Wang, Tao, Liu, Wen, Wang, Lijing, Hao, Ling, Ju, Mengwei, Xiao, Rong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Cell and Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7732486/
https://ncbi.nlm.nih.gov/pubmed/33330456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.580599
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