Adult-Onset Anti-Citrullinated Peptide Antibody-Negative Destructive Rheumatoid Arthritis Is Characterized by a Disease-Specific CD8+ T Lymphocyte Signature

Rheumatoid arthritis (RA) is a complex autoimmune disease targeting synovial joints. Traditionally, RA is divided into seropositive (SP) and seronegative (SN) disease forms, the latter consisting of an array of unrelated diseases with joint involvement. Recently, we described a severe form of SN-RA...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Kelkka, Tiina, Savola, Paula, Bhattacharya, Dipabarna, Huuhtanen, Jani, Lönnberg, Tapio, Kankainen, Matti, Paalanen, Kirsi, Tyster, Mikko, Lepistö, Maija, Ellonen, Pekka, Smolander, Johannes, Eldfors, Samuli, Yadav, Bhagwan, Khan, Sofia, Koivuniemi, Riitta, Sjöwall, Christopher, Elo, Laura L., Lähdesmäki, Harri, Maeda, Yuka, Nishikawa, Hiroyoshi, Leirisalo-Repo, Marjatta, Sokka-Isler, Tuulikki, Mustjoki, Satu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7732449/
https://ncbi.nlm.nih.gov/pubmed/33329548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.578848
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