Adult-Onset Anti-Citrullinated Peptide Antibody-Negative Destructive Rheumatoid Arthritis Is Characterized by a Disease-Specific CD8+ T Lymphocyte Signature

Rheumatoid arthritis (RA) is a complex autoimmune disease targeting synovial joints. Traditionally, RA is divided into seropositive (SP) and seronegative (SN) disease forms, the latter consisting of an array of unrelated diseases with joint involvement. Recently, we described a severe form of SN-RA...

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Vydáno v:Front Immunol
Hlavní autoři: Kelkka, Tiina, Savola, Paula, Bhattacharya, Dipabarna, Huuhtanen, Jani, Lönnberg, Tapio, Kankainen, Matti, Paalanen, Kirsi, Tyster, Mikko, Lepistö, Maija, Ellonen, Pekka, Smolander, Johannes, Eldfors, Samuli, Yadav, Bhagwan, Khan, Sofia, Koivuniemi, Riitta, Sjöwall, Christopher, Elo, Laura L., Lähdesmäki, Harri, Maeda, Yuka, Nishikawa, Hiroyoshi, Leirisalo-Repo, Marjatta, Sokka-Isler, Tuulikki, Mustjoki, Satu
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7732449/
https://ncbi.nlm.nih.gov/pubmed/33329548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.578848
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