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Melatonin Suppresses Ferroptosis Induced by High Glucose via Activation of the Nrf2/HO-1 Signaling Pathway in Type 2 Diabetic Osteoporosis

Ferroptosis is recently identified, an iron- and reactive oxygen species- (ROS-) dependent form of regulated cell death. This study was designed to determine the existence of ferroptosis in the pathogenesis of type 2 diabetic osteoporosis and confirm that melatonin can inhibit the ferroptosis of ost...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Ma, Hongdong, Wang, Xindong, Zhang, Weilin, Li, Haitian, Zhao, Wei, Sun, Jun, Yang, Maowei
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7732386/
https://ncbi.nlm.nih.gov/pubmed/33343809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/9067610
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