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Comprehensive N- and O-glycosylation mapping of human coagulation factor V

BACKGROUND/OBJECTIVE: Coagulation factor V (FV), a multidomain glycoprotein, is an essential cofactor in the blood clotting cascade. FV deficiency is a rare bleeding disorder that results in poor clotting after an injury or surgery. The only treatment for the disease is infusions of fresh frozen pla...

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Bibliografiske detaljer
Udgivet i:J Thromb Haemost
Main Authors: Ma, Cheng, Liu, Ding, Li, Dong, Zhang, Junping, Xu, Xiao-Qian, Zhu, He, Wan, Xiu-Feng, Miao, Carol H., Konkle, Barbara A., Onigman, Philip, Xiao, Weidong, Li, Lei
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7732234/
https://ncbi.nlm.nih.gov/pubmed/32310329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14861
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