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Quality of CD8(+) T cell immunity evoked in lymph nodes is compartmentalized by route of antigen transport and functional in tumor context

Revealing the mechanisms that underlie the expansion of antitumor CD8(+) T cells that are associated with improved clinical outcomes is critical to improving immunotherapeutic management of melanoma. How the lymphatic system, which orchestrates the complex sensing of antigen by lymphocytes to mount...

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Detalles Bibliográficos
Publicado en:Sci Adv
Main Authors: O’Melia, M. J., Rohner, N. A., Manspeaker, M. P., Francis, D. M., Kissick, H. T., Thomas, S. N.
Formato: Artigo
Idioma:Inglês
Publicado: American Association for the Advancement of Science 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7732197/
https://ncbi.nlm.nih.gov/pubmed/33310857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abd7134
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