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Detecting strong signals in gene perturbation experiments: An adaptive approach with power guarantee and FDR control
The perturbation of a transcription factor should affect the expression levels of its direct targets. However, not all genes showing changes in expression are direct targets. To increase the chance of detecting direct targets, we propose a modified two-group model where the null group corresponds to...
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| Vydáno v: | J Am Stat Assoc |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7731979/ https://ncbi.nlm.nih.gov/pubmed/33311819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/01621459.2019.1635484 |
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