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Intermolecular Interactions in Crystal Structures of Imatinib-Containing Compounds

Imatinib, one of the most used therapeutic agents to treat leukemia, is an inhibitor that specifically blocks the activity of tyrosine kinases. The molecule of imatinib is flexible and contains several functional groups able to take part in H-bonding and hydrophobic interactions. Analysis of molecul...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Vologzhanina, Anna V., Ushakov, Ivan E., Korlyukov, Alexander A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7731260/
https://ncbi.nlm.nih.gov/pubmed/33255944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21238970
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