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Intermolecular Interactions in Crystal Structures of Imatinib-Containing Compounds

Imatinib, one of the most used therapeutic agents to treat leukemia, is an inhibitor that specifically blocks the activity of tyrosine kinases. The molecule of imatinib is flexible and contains several functional groups able to take part in H-bonding and hydrophobic interactions. Analysis of molecul...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Vologzhanina, Anna V., Ushakov, Ivan E., Korlyukov, Alexander A.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7731260/
https://ncbi.nlm.nih.gov/pubmed/33255944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21238970
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