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Intermolecular Interactions in Crystal Structures of Imatinib-Containing Compounds

Imatinib, one of the most used therapeutic agents to treat leukemia, is an inhibitor that specifically blocks the activity of tyrosine kinases. The molecule of imatinib is flexible and contains several functional groups able to take part in H-bonding and hydrophobic interactions. Analysis of molecul...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Vologzhanina, Anna V., Ushakov, Ivan E., Korlyukov, Alexander A.
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7731260/
https://ncbi.nlm.nih.gov/pubmed/33255944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21238970
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