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Cyclodextrin-Based Nanostructure Efficiently Delivers siRNA to Glioblastoma Cells Preferentially via Macropinocytosis

Small interfering ribonucleic acid (siRNA) has the potential to revolutionize therapeutics since it can knockdown very efficiently the target protein. It is starting to be widely used to interfere with cell infection by HIV. However, naked siRNAs are unable to get into the cell, requiring the use of...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Manzanares, Darío, Pérez-Carrión, María Dolores, Jiménez Blanco, José Luis, Ortiz Mellet, Carmen, García Fernández, José Manuel, Ceña, Valentín
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7731237/
https://ncbi.nlm.nih.gov/pubmed/33291321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21239306
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