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Epigenetic Targets for Oligonucleotide Therapies of Pulmonary Arterial Hypertension
Arterial wall remodeling underlies increased pulmonary vascular resistance and right heart failure in pulmonary arterial hypertension (PAH). None of the established vasodilator drug therapies for PAH prevents or reverse established arterial wall thickening, stiffening, and hypercontractility. Theref...
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| 發表在: | Int J Mol Sci |
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| 主要作者: | |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
MDPI
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7731052/ https://ncbi.nlm.nih.gov/pubmed/33287230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21239222 |
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