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Epigenetic Targets for Oligonucleotide Therapies of Pulmonary Arterial Hypertension
Arterial wall remodeling underlies increased pulmonary vascular resistance and right heart failure in pulmonary arterial hypertension (PAH). None of the established vasodilator drug therapies for PAH prevents or reverse established arterial wall thickening, stiffening, and hypercontractility. Theref...
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| Publicado no: | Int J Mol Sci |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7731052/ https://ncbi.nlm.nih.gov/pubmed/33287230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21239222 |
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