Reduced Biliverdin Reductase-A Expression in Visceral Adipose Tissue is Associated with Adipocyte Dysfunction and NAFLD in Human Obesity

Biliverdin reductase A (BVR-A) is an enzyme involved in the regulation of insulin signalling. Knockout (KO) mice for hepatic BVR-A, on a high-fat diet, develop more severe glucose impairment and hepato-steatosis than the wild type, whereas loss of adipocyte BVR-A is associated with increased viscera...

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Publicat a:Int J Mol Sci
Autors principals: Ceccarelli, Valentina, Barchetta, Ilaria, Cimini, Flavia Agata, Bertoccini, Laura, Chiappetta, Caterina, Capoccia, Danila, Carletti, Raffaella, Di Cristofano, Claudio, Silecchia, Gianfranco, Fontana, Mario, Leonetti, Frida, Lenzi, Andrea, Baroni, Marco Giorgio, Barone, Eugenio, Cavallo, Maria Gisella
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730815/
https://ncbi.nlm.nih.gov/pubmed/33260451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21239091
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