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Hepcidin-ferroportin axis in health and disease
Hepcidin is central to regulation of iron metabolism. Its effect on a cellular level involves binding ferroportin, the main iron export protein, resulting in its internalization and degradation and leading to iron sequestration within ferroportin-expressing cells. Aberrantly increased hepcidin leads...
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| Udgivet i: | Vitam Horm |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7730607/ https://ncbi.nlm.nih.gov/pubmed/30798811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.vh.2019.01.002 |
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