Insight into Cisplatin-Resistance Signaling of W1 Ovarian Cancer Cells Emerges mTOR and HSP27 as Targets for Sensitization Strategies

The microenvironment possesses a strong impact on the tumor chemoresistance when cells bind to components of the extracellular matrix. Here we elucidate the signaling pathways of cisplatin resistance in W1 ovarian cancer cells binding to collagen type 1 (COL1) and signaling interference with constit...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Wantoch von Rekowski, Kathleen, König, Philipp, Henze, Svenja, Schlesinger, Martin, Zawierucha, Piotr, Januchowski, Radosław, Bendas, Gerd
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730285/
https://ncbi.nlm.nih.gov/pubmed/33287446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21239240
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