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Mechanisms of Matrix-Induced Chemoresistance of Breast Cancer Cells—Deciphering Novel Potential Targets for a Cell Sensitization

Tumor cell binding to microenvironment components such as collagen type 1 (COL1) attenuates the sensitivity to cytotoxic drugs like cisplatin (CDDP) or mitoxantrone (MX), referred to as cell adhesion mediated drug resistance (CAM-DR). CAM-DR is considered as the onset for resistance mutations, but u...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Jakubzig, Bastian, Baltes, Fabian, Henze, Svenja, Schlesinger, Martin, Bendas, Gerd
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6315379/
https://ncbi.nlm.nih.gov/pubmed/30563275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10120495
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