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On the Single-Crystal Structure of Tenofovir Alafenamide Mono-Fumarate: A Metastable Phase Featuring a Mixture of Co-Crystal and Salt

Tenofovir alafenamide (TAF) is a prodrug of tenofovir as a potent nucleotide reverse transcriptase inhibitor. It serves as the key component of Genvoya(®) for the first-line treatment of human immunodeficiency virus infection (HIV) and is the active component of Vemlidy(®) for the treatment of chron...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Wang, Jian-Wei, Liu, Lu, Yu, Ka-Xi, Bai, Hong-Zhen, Zhou, Jun, Zhang, Wen-Hua, Hu, Xiurong, Tang, Guping
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730268/
https://ncbi.nlm.nih.gov/pubmed/33287166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21239213
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