Dihydrotanshinone, a Natural Diterpenoid, Preserves Blood-Retinal Barrier Integrity via P2X7 Receptor

Activation of P2X7 signaling, due to high glucose levels, leads to blood retinal barrier (BRB) breakdown, which is a hallmark of diabetic retinopathy (DR). Furthermore, several studies report that high glucose (HG) conditions and the related activation of the P2X7 receptor (P2X7R) lead to the over-e...

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Publicat a:Int J Mol Sci
Autors principals: Fresta, Claudia Giuseppina, Caruso, Giuseppe, Fidilio, Annamaria, Platania, Chiara Bianca Maria, Musso, Nicolò, Caraci, Filippo, Drago, Filippo, Bucolo, Claudio
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730037/
https://ncbi.nlm.nih.gov/pubmed/33291318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21239305
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