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Novel ophthalmic formulation of myriocin: implications in retinitis pigmentosa

Myriocin is an antibiotic derived from Mycelia sterilia, and is a potent inhibitor of serine palmitoyltransferase, the enzyme involved in the first step of sphingosine synthesis. Myriocin, inhibiting ceramide synthesis, has a great potential for treatment of diseases characterized by high ceramide l...

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Bibliografiske detaljer
Udgivet i:Drug Deliv
Main Authors: Platania, Chiara Bianca Maria, Dei Cas, Michele, Cianciolo, Simona, Fidilio, Annamaria, Lazzara, Francesca, Paroni, Rita, Pignatello, Rosario, Strettoi, Enrica, Ghidoni, Riccardo, Drago, Filippo, Bucolo, Claudio
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6419690/
https://ncbi.nlm.nih.gov/pubmed/30883241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2019.1574936
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