Strand Displacement Activity of PrimPol

Human PrimPol is a unique enzyme possessing DNA/RNA primase and DNA polymerase activities. In this work, we demonstrated that PrimPol efficiently fills a 5-nt gap and possesses the conditional strand displacement activity stimulated by Mn(2+) ions and accessory replicative proteins RPA and PolDIP2....

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Boldinova, Elizaveta O., Belousova, Ekaterina A., Gagarinskaya, Diana I., Maltseva, Ekaterina A., Khodyreva, Svetlana N., Lavrik, Olga I., Makarova, Alena V.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7729601/
https://ncbi.nlm.nih.gov/pubmed/33261049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21239027
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