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Optimization of the spherical integrity for sustained-release alginate microcarriers-encapsulated doxorubicin by the Taguchi method

This study aimed to develop biodegradable calcium alginate microcarriers with uniform particle size and spherical integrity for sustained-release targeting transarterial chemoembolization. To determine related parameters including the ratio of cross-linking volume (sodium alginate: CaCl(2)), concent...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Pan, C. T., Chien, S. T., Chiang, T. C., Yen, C. K., Wang, S. Y., Wen, Z. H., Yu, C. Y., Shiue, Y. L.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7729399/
https://ncbi.nlm.nih.gov/pubmed/33303895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78813-1
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