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Applying the Taguchi Design for Optimized Formulation of Sustained Release Gliclazide Chitosan Beads: An In Vitro/In Vivo Study

Gliclazide is a second generation of hypoglycemic sulfonylurea and acts selectively on pancreatic β cell to control diabetes mellitus. The objective of this study was to produce a controlled release system of gliclazide using chitosan beads. Chitosan beads were produced by dispersion technique using...

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Detalhes bibliográficos
Main Authors: Varshosaz, J., Tavakoli, N., Minayian, M., Rahdari, N.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663681/
https://ncbi.nlm.nih.gov/pubmed/19205888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-009-9191-8
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