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Aspirin alleviates denervation-induced muscle atrophy via regulating the Sirt1/PGC-1α axis and STAT3 signaling

BACKGROUND: Our prior studies have shown that inflammation may play an important triggering role during the process of denervated muscle atrophy. The nonsteroidal anti-inflammatory drug aspirin exhibits the effect of anti-inflammatory factors. This study will investigate the protective effect of asp...

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Bibliografske podrobnosti
izdano v:Ann Transl Med
Main Authors: Wan, Qiuxian, Zhang, Lilei, Huang, Ziwei, Zhang, Haiyan, Gu, Jing, Xu, Hua, Yang, Xiaoming, Shen, Yuntian, Law, Betty Yuen-Kwan, Zhu, Jianwei, Sun, Hualin
Format: Artigo
Jezik:Inglês
Izdano: AME Publishing Company 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7729378/
https://ncbi.nlm.nih.gov/pubmed/33313269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm-20-5460
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