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Sodium–Taste Cells Require Skn-1a for Generation and Share Molecular Features with Sweet, Umami, and Bitter Taste Cells

Taste buds are maintained via continuous turnover of taste bud cells derived from local epithelial stem cells. A transcription factor Skn-1a (also known as Pou2f3) is required for the generation of sweet, umami (savory), and bitter taste cells that commonly express TRPM5 and CALHM ion channels. Here...

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Pubblicato in:eNeuro
Autori principali: Ohmoto, Makoto, Jyotaki, Masafumi, Foskett, J. Kevin, Matsumoto, Ichiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7729297/
https://ncbi.nlm.nih.gov/pubmed/33219051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0385-20.2020
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