Total Flavonoids of Rhizoma Drynariae Enhances Angiogenic-Osteogenic Coupling During Distraction Osteogenesis by Promoting Type H Vessel Formation Through PDGF-BB/PDGFR-β Instead of HIF-1α/ VEGF Axis

Background: Total flavonoids of Rhizoma Drynariae (TFRD), extracted from the kidney-tonifying traditional Chinese medicine Rhizoma Rrynariae, has been proved to be effective in treating osteoporosis, bone fractures and defects. However, pharmacological effects of TFRD on type H vessels, angiogenic-o...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Pharmacol
Auteurs principaux: Shen, Zhen, Chen, Zehua, Li, Zige, Zhang, Yan, Jiang, Tao, Lin, Haixiong, Huang, Minling, Chen, Huamei, Feng, Junjie, Jiang, Ziwei
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Pharmacology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7729076/
https://ncbi.nlm.nih.gov/pubmed/33328980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.503524
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