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Viral macrodomains: a structural and evolutionary assessment of the pharmacological potential

Viral macrodomains possess the ability to counteract host ADP-ribosylation, a post-translational modification implicated in the creation of an antiviral environment via immune response regulation. This brought them into focus as promising therapeutic targets, albeit the close homology to some of the...

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Vydáno v:Open Biol
Hlavní autoři: Rack, Johannes Gregor Matthias, Zorzini, Valentina, Zhu, Zihan, Schuller, Marion, Ahel, Dragana, Ahel, Ivan
Médium: Artigo
Jazyk:Inglês
Vydáno: The Royal Society 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7729036/
https://ncbi.nlm.nih.gov/pubmed/33202171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.200237
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