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Viral macrodomains: a structural and evolutionary assessment of the pharmacological potential

Viral macrodomains possess the ability to counteract host ADP-ribosylation, a post-translational modification implicated in the creation of an antiviral environment via immune response regulation. This brought them into focus as promising therapeutic targets, albeit the close homology to some of the...

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Библиографические подробности
Опубликовано в: :Open Biol
Главные авторы: Rack, Johannes Gregor Matthias, Zorzini, Valentina, Zhu, Zihan, Schuller, Marion, Ahel, Dragana, Ahel, Ivan
Формат: Artigo
Язык:Inglês
Опубликовано: The Royal Society 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7729036/
https://ncbi.nlm.nih.gov/pubmed/33202171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.200237
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