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Pushing the Envelope in Psoriasis: Late Cornified Envelope Proteins Possess Antimicrobial Activity
Deletion of late cornified envelope (LCE) genes LCE3B and LCE3C (LCE3B/C-del) is a psoriasis risk factor linked to the major psoriasis risk gene HLA-C*06. Niehues et al. demonstrate that LCE3B/C-del leads to increased keratinocyte LCE3A expression. They also show that LCE3A/B/C possess antimicrobial...
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| Veröffentlicht in: | J Invest Dermatol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7727264/ https://ncbi.nlm.nih.gov/pubmed/29055413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2017.08.026 |
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