Pushing the Envelope in Psoriasis: Late Cornified Envelope Proteins Possess Antimicrobial Activity

Deletion of late cornified envelope (LCE) genes LCE3B and LCE3C (LCE3B/C-del) is a psoriasis risk factor linked to the major psoriasis risk gene HLA-C*06. Niehues et al. demonstrate that LCE3B/C-del leads to increased keratinocyte LCE3A expression. They also show that LCE3A/B/C possess antimicrobial...

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Detaylı Bibliyografya
Yayımlandı:J Invest Dermatol
Asıl Yazarlar: Archer, Nathan K., Dilolli, Migena N., Miller, Lloyd S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7727264/
https://ncbi.nlm.nih.gov/pubmed/29055413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2017.08.026
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